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Exogenous Sphingosine-1-Phosphate Boosts Acclimatization in Rats Exposed to Acute Hypobaric Hypoxia: Assessment of Haematological and Metabolic Effects

BACKGROUND: The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxi...

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Detalhes bibliográficos
Main Authors: Chawla, Sonam, Rahar, Babita, Singh, Mrinalini, Bansal, Anju, Saraswat, Deepika, Saxena, Shweta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041657/
https://ncbi.nlm.nih.gov/pubmed/24887065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098025
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