Induction of Neutralizing Antibody Response against Four Dengue Viruses in Mice by Intramuscular Electroporation of Tetravalent DNA Vaccines

DNA vaccine against dengue is an interesting strategy for a prime/boost approach. This study evaluated neutralizing antibody (NAb) induction of a dengue tetravalent DNA (TDNA) vaccine candidate administered by intramuscular-electroporation (IM-EP) and the benefit of homologous TDNA boosting in mice....

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Detalhes bibliográficos
Main Authors: Prompetchara, Eakachai, Ketloy, Chutitorn, Keelapang, Poonsook, Sittisombut, Nopporn, Ruxrungtham, Kiat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041562/
https://ncbi.nlm.nih.gov/pubmed/24887426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092643
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