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Prokaryotic Argonautes defend genomes against invasive DNA

Argonaute proteins are central players in small RNA-mediated silencing mechanisms such as RNA interference (RNAi), microRNA repression and piRNA-mediated transposon silencing. In eukaryotes, Argonautes bind small RNAs that guide them to RNA targets in order to regulate gene expression and repress in...

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Hlavní autoři: Hur, Junho K., Olovnikov, Ivan, Aravin, Alexei A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041519/
https://ncbi.nlm.nih.gov/pubmed/24836995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.04.006
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