The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer

In prostate cancer (PC), the androgen receptor (AR) is a key transcription factor at all disease stages, including the advanced stage of castrate-resistant prostate cancer (CRPC). In the present study, we show that GABPα, an ETS factor that is up-regulated in PC, is an AR-interacting transcription f...

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Detalhes bibliográficos
Main Authors: Sharma, Naomi L., Massie, Charlie E., Butter, Falk, Mann, Matthias, Bon, Helene, Ramos-Montoya, Antonio, Menon, Suraj, Stark, Rory, Lamb, Alastair D., Scott, Helen E., Warren, Anne Y., Neal, David E., Mills, Ian G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041454/
https://ncbi.nlm.nih.gov/pubmed/24753418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku281
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