The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu

Dnmt2 enzymes are conserved in eukaryotes, where they methylate C38 of tRNA-Asp with high activity. Here, the activity of one of the very few prokaryotic Dnmt2 homologs from Geobacter species (GsDnmt2) was investigated. GsDnmt2 was observed to methylate tRNA-Asp from flies and mice. Unexpectedly, it...

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Main Authors: Shanmugam, Raghuvaran, Aklujkar, Muktak, Schäfer, Matthias, Reinhardt, Richard, Nickel, Olaf, Reuter, Gunter, Lovley, Derek R., Ehrenhofer-Murray, Ann, Nellen, Wolfgang, Ankri, Serge, Helm, Mark, Jurkowski, Tomasz P., Jeltsch, Albert
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041430/
https://ncbi.nlm.nih.gov/pubmed/24711368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku256
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