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Sclerostin is a direct target of osteoblast-specific transcription factor osterix
Osterix (Osx) is an osteoblast-specific transcription factor required for osteoblast differentiation and bone formation. Osx knock-out mice lack bone completely. Recent findings that Osx inhibits Wnt signaling provide a feedback control mechanism involved in bone formation. Mechanisms of Osx inhibit...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041335/ https://ncbi.nlm.nih.gov/pubmed/20816666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.08.128 |
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