Experimental prestorage filtration removes antibodies and decreases lipids in RBC supernatants mitigating TRALI in vivo

Transfusion-related acute lung injury (TRALI) remains a significant cause of transfusion-related mortality with red cell transfusion. We hypothesize that prestorage filtration may reduce proinflammatory activity in the red blood cell (RBC) supernatant and prevent TRALI. Filters were manufactured for...

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Detalhes bibliográficos
Main Authors: Silliman, Christopher C., Kelher, Marguerite R., Khan, Samina Y., LaSarre, Monica, West, F. Bernadette, Land, Kevin J., Mish, Barbara, Ceriano, Linda, Sowemimo-Coker, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041171/
https://ncbi.nlm.nih.gov/pubmed/24747436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-532424
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