Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis

In multiple sclerosis, in which brain tissue becomes permeable to blood proteins, extravascular fibrin deposition correlates with sites of inflammatory demyelination and axonal damage. To examine the role of fibrin in neuroinflammatory demyelination, we depleted fibrin in two tumor necrosis factor t...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Akassoglou, Katerina, Adams, Ryan A., Bauer, Jan, Mercado, Peter, Tseveleki, Vivian, Lassmann, Hans, Probert, Lesley, Strickland, Sidney
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404108/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15096619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0303859101
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!