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Lactosylceramide recruits PKCα/ε and phospholipase A(2) to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells
Despite the importance of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in the adhesion and diapedesis of monocytes/lymphocytes, little is known about the mechanisms by which it is regulated. We explored the role of a glycosphingolipid, lactosylceramide (LacCer), in modulating PECAM-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404072/ https://ncbi.nlm.nih.gov/pubmed/15084746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308684101 |
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