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Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson's model

Genetic and idiopathic forms of Parkinson's disease (PD) are characterized by loss of dopamine (DA) neurons and typically the formation of protein inclusions containing the alpha-synuclein (α-syn) protein. Environmental contributors to PD remain largely unresolved but toxins, such as paraquat o...

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Hlavní autoři: Ray, A, Martinez, B A, Berkowitz, L A, Caldwell, G A, Caldwell, K A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040705/
https://ncbi.nlm.nih.gov/pubmed/24407237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.513
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