Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment

The Wnt1 protein, a secreted ligand that activates Wnt signaling pathways, contributes to the self-renewal of cancer stem cells (CSCs) and thus may be a major determinant of tumor progression and chemoresistance. In a series of gastric cancer specimens, we found strong correlations among Wnt1 expres...

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Main Authors: Mao, J, Fan, S, Ma, W, Fan, P, Wang, B, Zhang, J, Wang, H, Tang, B, Zhang, Q, Yu, X, Wang, L, Song, B, Li, L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040703/
https://ncbi.nlm.nih.gov/pubmed/24481453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.515
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