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Simulations of the role of water in the protein-folding mechanism

There are many unresolved questions regarding the role of water in protein folding. Does water merely induce hydrophobic forces, or does the discrete nature of water play a structural role in folding? Are the nonadditive aspects of water important in determining the folding mechanism? To help to add...

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Autori principali: Rhee, Young Min, Sorin, Eric J., Jayachandran, Guha, Lindahl, Erik, Pande, Vijay S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC404066/
https://ncbi.nlm.nih.gov/pubmed/15090647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307898101
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