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Integrin inhibition promotes atypical anoikis in glioma cells

Integrins regulate cellular adhesion and transmit signals important for cell survival, proliferation and motility. They are expressed by glioma cells and may contribute to their malignant phenotype. Integrin inhibition may therefore represent a promising therapeutic strategy. GL-261 and SMA-560 glio...

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Detalhes bibliográficos
Main Authors: Silginer, M, Weller, M, Ziegler, U, Roth, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040659/
https://ncbi.nlm.nih.gov/pubmed/24457956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.543
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