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Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling
It is known that many chemotherapeutics induce cellular apoptosis over hours to days. During apoptosis, numerous cellular proteases are activated, most canonically the caspases. We speculated that detection of proteolytic fragments released from apoptotic cells into the peripheral blood may serve as...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040605/ https://ncbi.nlm.nih.gov/pubmed/24821784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405987111 |
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