Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

Using methodology developed herein, it is found that reactive persulfides and polysulfides are formed endogenously from both small molecule species and proteins in high amounts in mammalian cells and tissues. These reactive sulfur species were biosynthesized by two major sulfurtransferases: cystathi...

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Detalles Bibliográficos
Autores principales: Ida, Tomoaki, Sawa, Tomohiro, Ihara, Hideshi, Tsuchiya, Yukihiro, Watanabe, Yasuo, Kumagai, Yoshito, Suematsu, Makoto, Motohashi, Hozumi, Fujii, Shigemoto, Matsunaga, Tetsuro, Yamamoto, Masayuki, Ono, Katsuhiko, Devarie-Baez, Nelmi O., Xian, Ming, Fukuto, Jon M., Akaike, Takaaki
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040604/
https://ncbi.nlm.nih.gov/pubmed/24733942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321232111
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