Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets

Mechanisms that control the levels and activities of reactive oxygen species (ROS) in normal human mammary cells are poorly understood. We show that purified normal human basal mammary epithelial cells maintain low levels of ROS primarily by a glutathione-dependent but inefficient antioxidant mechan...

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Main Authors: Kannan, Nagarajan, Nguyen, Long V., Makarem, Maisam, Dong, Yifei, Shih, Kingsley, Eirew, Peter, Raouf, Afshin, Emerman, Joanne T., Eaves, Connie J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040592/
https://ncbi.nlm.nih.gov/pubmed/24821780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403813111
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