Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

BACKGROUND: Pulmonary-delivered gene therapy promises to mitigate vaccine safety issues and reduce the need for needles and skilled personnel to use them. While plasmid DNA (pDNA) offers a rapid route to vaccine production without side effects or reliance on cold chain storage, its delivery to the l...

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Hauptverfasser: Rajapaksa, Anushi E, Ho, Jenny J, Qi, Aisha, Bischof, Rob, Nguyen, Tri-Hung, Tate, Michelle, Piedrafita, David, McIntosh, Michelle P, Yeo, Leslie Y, Meeusen, Els, Coppel, Ross L, Friend, James R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040411/
https://ncbi.nlm.nih.gov/pubmed/24884387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-15-60
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