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Toll-like Receptor 4 (TLR4) modulation by synthetic and natural compounds: an update
Toll-like receptor 4 (TLR4), together with MD-2, binds bacterial endotoxins (E) with high affinity, triggering formation of the activated homodimer (E-MD-2-TLR4)(2). Activated TLR4 induces intracellular signaling leading to activation of transcription factors that result in cytokine and chemokine pr...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040398/ https://ncbi.nlm.nih.gov/pubmed/24188011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401006s |
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