A Phase III Randomized, Placebo-Controlled Study of Topical Amitriptyline and Ketamine for Chemotherapy-Induced Peripheral Neuropathy (CIPN): A University of Rochester CCOP Study of 462 Cancer Survivors

PURPOSE: Chemotherapy-induced peripheral neuropathy (CIPN) occurs in as high as 70% of patients receiving certain types of chemotherapy agents. The FDA has yet to approve a therapy for CIPN. The aim of this multicenter, phase III, randomized, double-blind, placebo-controlled trial was to investigate...

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Autori principali: Gewandter, Jennifer S., Mohile, Supriya G., Heckler, Charles E., Ryan, Julie L., Kirshner, Jeffrey J., Flynn, Patrick J., Hopkins, Judith O., Morrow, Gary R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040331/
https://ncbi.nlm.nih.gov/pubmed/24531792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-014-2158-7
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