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IgE–mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation

BACKGROUND: Mast cells play a critical role in inflammatory skin diseases through releasing pro-inflammatory mediators; however, few therapies directly target these cells. In 1878, the use of topical Thymol, a now recognized potent agonist for Transient Receptor Potential (TRP) channels, was first d...

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Autori principali: Wechsler, Joshua B., Hsu, Chia-Lin, Bryce, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040322/
https://ncbi.nlm.nih.gov/pubmed/24486068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.12.024
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