Prostaglandin E(2) resistance in granulocytes from patients with aspirin-exacerbated respiratory disease

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is an inflammatory condition of the respiratory tract and is characterized by overproduction of leukotrienes (LT) and large numbers of circulating granulocyte-platelet complexes. LT production can be suppressed by prostaglandin E(2) (PGE(2))...

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Bibliographic Details
Main Authors: Laidlaw, Tanya M., Cutler, Anya J., Kidder, Molly S., Liu, Tao, Cardet, Juan Carlos, Chhay, Heng, Feng, Chunli, Boyce, Joshua A.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040319/
https://ncbi.nlm.nih.gov/pubmed/24486071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.12.1034
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