Zoledronic acid has differential anti-tumour activity in the pre-and post-menopausal bone microenvironment in vivo

PURPOSE: Clinical trials in early breast cancer have suggested that benefits of adjuvant bone targeted treatments are restricted to women with established menopause. We developed models that mimic pre- and post-menopausal status to investigate effects of altered bone turnover on growth of disseminat...

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Hauptverfasser: Ottewell, Penelope D, Wang, Ning, Brown, Hannah K, Reeves, Kimberly J, Fowles, C Anne, Croucher, Peter I, Eaton, Colby L, Holen, Ingunn
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040234/
https://ncbi.nlm.nih.gov/pubmed/24687923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1246
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