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The adenosine transporter, ENT1, in cardiomyocytes is sensitive to inhibition by ethanol in a kinase-dependent manner: implications for ethanol-dependent cardioprotection and nucleoside analog drug cytotoxicity

The adenosine transporter 1 (ENT1) transports nucleosides, such as adenosine, and cytotoxic nucleoside analog drugs. ENT1 is well established to play a role in adenosinergic signaling in the cardiovascular system by modulating adenosine levels. Moderate ethanol consumption is cardioprotective and un...

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Bibliographic Details
Main Authors: Ramadan, Azza, Naydenova, Zlatina, Stevanovic, Katarina, Rose, Jennifer B., Coe, Imogen R.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040176/
https://ncbi.nlm.nih.gov/pubmed/24163005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-013-9391-2
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