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T cells increase before zoster and PD-1 expression increases at the time of zoster in immunosuppressed non-human primates latently infected with simian varicella virus

Like varicella zoster virus in humans, simian varicella virus (SVV) becomes latent in ganglionic neurons along the entire neuraxis and reactivates in immunosuppressed monkeys. Five rhesus macaques were inoculated with SVV; 142 days later (latency), 4 monkeys were immunosuppressed and T cells were an...

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Detalhes bibliográficos
Main Authors: James, Stephanie F., Traina-Dorge, Vicki, Deharo, Eileen, Wellish, Mary, Palmer, Brent, Gilden, Don, Mahalingam, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040158/
https://ncbi.nlm.nih.gov/pubmed/24549971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-014-0237-7
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