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T cells increase before zoster and PD-1 expression increases at the time of zoster in immunosuppressed non-human primates latently infected with simian varicella virus

Like varicella zoster virus in humans, simian varicella virus (SVV) becomes latent in ganglionic neurons along the entire neuraxis and reactivates in immunosuppressed monkeys. Five rhesus macaques were inoculated with SVV; 142 days later (latency), 4 monkeys were immunosuppressed and T cells were an...

詳細記述

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書誌詳細
主要な著者: James, Stephanie F., Traina-Dorge, Vicki, Deharo, Eileen, Wellish, Mary, Palmer, Brent, Gilden, Don, Mahalingam, Ravi
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040158/
https://ncbi.nlm.nih.gov/pubmed/24549971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-014-0237-7
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