Tyrosine Phosphorylation of Sprouty Proteins Regulates Their Ability to Inhibit Growth Factor Signaling: A Dual Feedback Loop

Sprouty proteins are recently identified receptor tyrosine kinase (RTK) inhibitors potentially involved in many developmental processes. Here, we report that Sprouty proteins become tyrosine phosphorylated after growth factor treatment. We identified Tyr55 as a key residue for Sprouty2 phosphorylati...

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Main Authors: Mason, Jacqueline M., Morrison, Debra J., Bassit, Bhramdeo, Dimri, Manjari, Band, Hamid, Licht, Jonathan D., Gross, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2004
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404014/
https://ncbi.nlm.nih.gov/pubmed/15004239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0503
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