Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study

OBJECTIVE: Common variants at the 2q36.3-IRS1 locus are associated with insulin resistance (IR), type 2 diabetes (T2D) and coronary artery disease (CAD) in large-scale association studies. We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits. ME...

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Main Authors: Lim, Soo, Hong, Jaeyoung, Liu, Ching-Ti, Hivert, Marie-France, White, Charles C., Murabito, Joanne M., O'Donnell, Christopher J., Dupuis, Josée, Florez, Jose C., Meigs, James B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040123/
https://ncbi.nlm.nih.gov/pubmed/23659870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2013.03.037
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