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Phosphorylation of c-Cbl and p85 PI3K Driven by All-trans Retinoic Acid and CD38 Depends on Lyn Kinase Activity

The leukocyte antigen CD38 is expressed after all-trans retinoic acid (ATRA) treatment in HL-60 myelogenous leukemia cells and promotes induced myeloid differentiation when overexpressed. We found that Vav1 and SLP-76 associate with CD38 in two cell lines, and that these proteins complex with Lyn, a...

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Detalhes bibliográficos
Main Authors: Congleton, Johanna, Shen, Miaoqing, MacDonald, Robert, Malavasi, Fabio, Yen, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039659/
https://ncbi.nlm.nih.gov/pubmed/24686085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.03.021
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