Prohibitin Expression Deregulation in Gastric Cancer Is Associated with the 3′ Untranslated Region 1630 C>T Polymorphism and Copy Number Variation

PHB is a reported oncogene and tumor suppressor in gastric cancer. Here, we evaluated whether the PHB copy number and the rs6917 polymorphism affect its expression in gastric cancer. Down-regulation and up-regulation of PHB were observed in the evaluated tumors. Reduced expression was associated wit...

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Detalhes bibliográficos
Main Authors: Leal, Mariana Ferreira, Cirilo, Priscila Daniele Ramos, Mazzotti, Tatiane Katsue Furuya, Calcagno, Danielle Queiroz, Wisnieski, Fernanda, Demachki, Samia, Martinez, Margarita Cortes, Assumpção, Paulo Pimentel, Chammas, Roger, Burbano, Rommel Rodríguez, Smith, Marília Cardoso
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039508/
https://ncbi.nlm.nih.gov/pubmed/24879411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098583
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