Pancreatic Cancer Cell Glycosylation Regulates Cell Adhesion and Invasion through the Modulation of α2β1 Integrin and E-Cadherin Function

In our previous studies we have described that ST3Gal III transfected pancreatic adenocarcinoma Capan-1 and MDAPanc-28 cells show increased membrane expression levels of sialyl-Lewis x (SLe(x)) along with a concomitant decrease in α2,6-sialic acid compared to control cells. Here we have addressed th...

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Main Authors: Bassagañas, Sònia, Carvalho, Sandra, Dias, Ana M., Pérez-Garay, Marta, Ortiz, M. Rosa, Figueras, Joan, Reis, Celso A., Pinho, Salomé S., Peracaula, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039506/
https://ncbi.nlm.nih.gov/pubmed/24878505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098595
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