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Likelihood-Based Approach to Gene Set Enrichment Analysis with a Finite Mixture Model
In this paper, we study a parametric modeling approach to gene set enrichment analysis. Existing methods have largely relied on nonparametric approaches employing, e.g., categorization, permutation or resampling-based significance analysis methods. These methods have proven useful yet might not be p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039382/ https://ncbi.nlm.nih.gov/pubmed/24891922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-012-9076-3 |
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