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Transcriptional regulation is insufficient to explain substrate-induced flux changes in Bacillus subtilis

One of the key ways in which microbes are thought to regulate their metabolism is by modulating the availability of enzymes through transcriptional regulation. However, the limited success of efforts to manipulate metabolic fluxes by rewiring the transcriptional network has cast doubt on the idea th...

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Main Authors: Chubukov, Victor, Uhr, Markus, Le Chat, Ludovic, Kleijn, Roelco J, Jules, Matthieu, Link, Hannes, Aymerich, Stephane, Stelling, Jörg, Sauer, Uwe
格式: Artigo
語言:Inglês
出版: European Molecular Biology Organization 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039378/
https://ncbi.nlm.nih.gov/pubmed/24281055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.66
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