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Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue

Long-term consumption of high-fat diets negatively interferes with metabolic status and promotes endothelial dysfunction and inflammation. In the cavernous tissue, these outcomes become conspicuous in the elderly and strongly affect penile erection, a vascular process highly dependent on local nitri...

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Detalhes bibliográficos
Main Authors: Tomada, I., Negrão, R., Almeida, H., Neves, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039277/
https://ncbi.nlm.nih.gov/pubmed/24105250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9591-2
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