Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

Upregulation of constitutively-active androgen receptor splice variants (AR-Vs) has been implicated in AR-driven tumor progression in castration-resistant prostate cancer. To date, functional studies of AR-Vs have been focused mainly on their ability to regulate gene expression independent of the fu...

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Autors principals: Cao, Bo, Qi, Yanfeng, Zhang, Guanyi, Xu, Duo, Zhan, Yang, Alvarez, Xavier, Guo, Zhiyong, Fu, Xueqi, Plymate, Stephen R., Sartor, Oliver, Zhang, Haitao, Dong, Yan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039237/
https://ncbi.nlm.nih.gov/pubmed/24722067
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