Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication

The extreme aggressiveness of pancreatic ductal adenocarcinoma (PDA) has been associated with blocked gap junctional intercellular communication (GJIC) and the presence of cancer stem cells (CSCs). We examined whether disturbed GJIC is responsible for a CSC phenotype in established and primary cance...

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Hauptverfasser: Forster, Tobias, Rausch, Vanessa, Zhang, Yiyao, Isayev, Orkhan, Heilmann, Katharina, Schoensiegel, Frank, Liu, Li, Nessling, Michelle, Richter, Karsten, Labsch, Sabrina, Nwaeburu, Clifford C., Mattern, Juergen, Gladkich, Jury, Giese, Nathalia, Werner, Jens, Schemmer, Peter, Gross, Wolfgang, Gebhard, Martha M., Gerhauser, Clarissa, Schaefer, Michael, Herr, Ingrid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039235/
https://ncbi.nlm.nih.gov/pubmed/24742583
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