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Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic
OBJECTIVE: To characterize the pharmacokinetics and pharmacogenetics of nifedipine in pregnancy. STUDY DESIGN: Pregnant women receiving oral nifedipine underwent steady-state pharmacokinetic testing over one dosing interval. DNA was obtained and genotyped for cytochrome P450 (CYP) 3A5, and CYP3A4*1B...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039203/ https://ncbi.nlm.nih.gov/pubmed/22875663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1323590 |
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