Statistical Design for Biospecimen Cohort Size in Proteomics-based Biomarker Discovery and Verification Studies

Protein biomarkers are needed to deepen our understanding of cancer biology and to improve our ability to diagnose, monitor and treat cancers. Important analytical and clinical hurdles must be overcome to allow the most promising protein biomarker candidates to advance into clinical validation studi...

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Hlavní autoři: Skates, Steven J., Gillette, Michael A., LaBaer, Joshua, Carr, Steven A., Anderson, N. Leigh, Liebler, Daniel C., Ransohoff, David, Rifai, Nader, Kondratovich, Marina, Težak, Živana, Mansfield, Elizabeth, Oberg, Ann L., Wright, Ian, Barnes, Grady, Gail, Mitchell, Mesri, Mehdi, Kinsinger, Christopher R., Rodriguez, Henry, Boja, Emily S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039197/
https://ncbi.nlm.nih.gov/pubmed/24063748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr400132j
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