Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation

The Janus kinase / signal transducer and activator of transcription (Jak/STAT) pathway can be activated by many different cytokines, among them all members of the Interleukin (IL-)6 family. Dysregulation of this pathway, resulting in its constitutive activation, is associated with chronic inflammati...

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Hlavní autoři: Aparicio-Siegmund, Samadhi, Sommer, Jan, Monhasery, Niloufar, Schwanbeck, Ralf, Keil, Eric, Finkenstädt, David, Pfeffer, Klaus, Rose-John, Stefan, Scheller, Jürgen, Garbers, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039151/
https://ncbi.nlm.nih.gov/pubmed/24742922
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