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Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine

Precision medicine depends on the accurate identification of actionable mutations in a tumor sample. It is unknown how heterogeneous the distribution of such mutations can be in a tumor. Morphological (i.e. histopathological) heterogeneity is well described in lung adenocarcinoma and has been specif...

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Autors principals: Wright, Gavin M., Do, Hongdo, Weiss, Jonathan, Alam, Naveed Z., Rathi, Vivek, Walkiewicz, Marzena, John, Thomas, Russell, Prudence A., Dobrovic, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039149/
https://ncbi.nlm.nih.gov/pubmed/24742923
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