C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2

Core 1 β1,3-galactosyltransferase (C1GALT1) transfers galactose (Gal) to N-acetylgalactosamine (GalNAc) to form Galβ1,3GalNAc (T antigen). Aberrant O-glycans, such as T antigen, are commonly found in colorectal cancer. However, the role of C1GALT1 in colorectal cancer remains unclear. Here we showed...

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Bibliographische Detailangaben
Hauptverfasser: Hung, Ji-Shiang, Huang, John, Lin, Yo-Chuen, Huang, Miao-Juei, Lee, Po-Huang, Lai, Hong-Shiee, Liang, Jin-Tung, Huang, Min-Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039148/
https://ncbi.nlm.nih.gov/pubmed/24758762
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