The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1

Patients with neuroblastoma due to N-Myc oncogene amplification have a high frequency of tumor metastasis. However, it is not clear how N-Myc induces cell migration, invasion and metastasis. The histone demethylase JMJD1A activates gene transcription by demethylating the lysine 9 residue of histone...

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Main Authors: Tee, Andrew E., Ling, Dora, Nelson, Charlotte, Atmadibrata, Bernard, Dinger, Marcel E., Xu, Ning, Mizukami, Tamio, Liu, Pei Y., Liu, Bing, Cheung, Belamy, Pasquier, Eddy, Haber, Michelle, Norris, Murray D., Suzuki, Takayoshi, Marshall, Glenn M., Liu, Tao
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039110/
https://ncbi.nlm.nih.gov/pubmed/24742640
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