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Regulation of Cop9 signalosome activity by the EF-hand Ca(2+)-binding protein tescalcin

The Ca(2+)-binding protein tescalcin is known to be involved in hematopoietic cell differentiation; however, this mechanism is poorly understood. Here, we identify CSN4 (subunit 4 of the COP9 signalosome) as a novel binding partner of tescalcin. The COP9 signalosome (CSN) is a multiprotein complex t...

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Detalhes bibliográficos
Main Authors: Levay, Konstantin, Slepak, Vladlen Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038942/
https://ncbi.nlm.nih.gov/pubmed/24659803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.139592
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