Large Scale RNAi Reveals the Requirement of Nuclear Envelope Breakdown for Nuclear Import of Human Papillomaviruses

A two-step, high-throughput RNAi silencing screen was used to identify host cell factors required during human papillomavirus type 16 (HPV16) infection. Analysis of validated hits implicated a cluster of mitotic genes and revealed a previously undetermined mechanism for import of the viral DNA (vDNA...

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Detalhes bibliográficos
Main Authors: Aydin, Inci, Weber, Susanne, Snijder, Berend, Samperio Ventayol, Pilar, Kühbacher, Andreas, Becker, Miriam, Day, Patricia M., Schiller, John T., Kann, Michael, Pelkmans, Lucas, Helenius, Ari, Schelhaas, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038628/
https://ncbi.nlm.nih.gov/pubmed/24874089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004162
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