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The Cytoplasmic Domain of Varicella-Zoster Virus Glycoprotein H Regulates Syncytia Formation and Skin Pathogenesis

The conserved herpesvirus fusion complex consists of glycoproteins gB, gH, and gL which is critical for virion envelope fusion with the cell membrane during entry. For Varicella Zoster Virus (VZV), the complex is necessary for cell-cell fusion and presumed to mediate entry. VZV causes syncytia forma...

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Autors principals: Yang, Edward, Arvin, Ann M., Oliver, Stefan L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038623/
https://ncbi.nlm.nih.gov/pubmed/24874654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004173
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