Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to produce viral particles upon ex vivo exposure...

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Detalhes bibliográficos
Main Authors: Mohammadi, Pejman, di Iulio, Julia, Muñoz, Miguel, Martinez, Raquel, Bartha, István, Cavassini, Matthias, Thorball, Christian, Fellay, Jacques, Beerenwinkel, Niko, Ciuffi, Angela, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038609/
https://ncbi.nlm.nih.gov/pubmed/24875931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004156
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