Severity of cough in idiopathic pulmonary fibrosis is associated with MUC5 B genotype

BACKGROUND: A polymorphism (rs35705950) in the promoter region of the mucin MUC5B is associated with both familial and sporadic forms of idiopathic pulmonary fibrosis. (IPF) We hypothesize that this common MUC5B variant will impact the expression of cough, a frequent disabling symptom seen in subjec...

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Hlavní autoři: Scholand, Mary Beth, Wolff, Roger, Crossno, Peter Fredrick, Sundar, Krishna, Winegar, Molly, Whipple, Spencer, Carey, Patrick, Sunchild, Nicholas, Coon, Hilary
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038402/
https://ncbi.nlm.nih.gov/pubmed/24667072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-9974-10-3
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