Severity of cough in idiopathic pulmonary fibrosis is associated with MUC5 B genotype

BACKGROUND: A polymorphism (rs35705950) in the promoter region of the mucin MUC5B is associated with both familial and sporadic forms of idiopathic pulmonary fibrosis. (IPF) We hypothesize that this common MUC5B variant will impact the expression of cough, a frequent disabling symptom seen in subjec...

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Detalhes bibliográficos
Main Authors: Scholand, Mary Beth, Wolff, Roger, Crossno, Peter Fredrick, Sundar, Krishna, Winegar, Molly, Whipple, Spencer, Carey, Patrick, Sunchild, Nicholas, Coon, Hilary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038402/
https://ncbi.nlm.nih.gov/pubmed/24667072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-9974-10-3
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