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Chemo- and Regioselective C(sp(3))–H Arylation of Unactivated Allylarenes via a Deprotonative Cross-coupling Process

The combination of aryl bromides, allylbenzene, base and a palladium catalyst usually results in a Heck reaction. Herein we combine these same reagents, but override the Heck pathway by employing a strong base. In the presence of LiN(SiMe(3))(2), allylbenzene derivatives undergo reversible deprotona...

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Autors principals: Hussain, Nusrah, Frensch, Gustavo, Zhang, Jiadi, Walsh, Patrick J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038169/
https://ncbi.nlm.nih.gov/pubmed/24574070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201309084
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