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Clone-Based Systematic Haplotyping (CSH): A Procedure for Physical Haplotyping of Whole Genomes

We present a novel methodology to determine the phase of single-nucleotide polymorphisms (SNPs) on a chromosome, which we term clone-based systematic haplotyping (CSH). The CSH procedure is based on separating the allelic chromosomes of a diploid genome by fosmid/cosmid cloning, and subsequent SNP t...

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Detalhes bibliográficos
Main Authors: Burgtorf, Carola, Kepper, Pamela, Hoehe, Margret, Schmitt, Carsten, Reinhardt, Richard, Lehrach, Hans, Sauer, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC403814/
https://ncbi.nlm.nih.gov/pubmed/14656974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1442303
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