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New drugs in multiple myeloma – role of carfilzomib and pomalidomide

Carfilzomib (CFZ), an epoxyketone with specific chymotrypsin-like activity, is a second-generation proteasome inhibitor with significant activity in patients with relapsed and refractory multiple myeloma. On July 20, 2012, the US Food and Drug Administration approved CFZ to treat patients with multi...

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Main Authors: Jurczyszyn, Artur, Legieć, Wojciech, Helbig, Grzegorz, Hus, Marek, Kyrcz-Krzemień, Sławomira, Skotnicki, Aleksander B.
Formato: Artigo
Idioma:Inglês
Publicado: Termedia Publishing House 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037992/
https://ncbi.nlm.nih.gov/pubmed/24876816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/wo.2014.40175
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