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Shuffling of Genes Within Low-Copy Repeats on 22q11 (LCR22) by Alu-Mediated Recombination Events During Evolution

Low-copy repeats, or segmental duplications, are highly dynamic regions in the genome. The low-copy repeats on chromosome 22q11.2 (LCR22) are a complex mosaic of genes and pseudogenes formed by duplication processes; they mediate chromosome rearrangements associated with velo-cardio-facial syndrome/...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Babcock, Melanie, Pavlicek, Adam, Spiteri, Elizabeth, Kashork, Catherine D., Ioshikhes, Ilya, Shaffer, Lisa G., Jurka, Jerzy, Morrow, Bernice E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC403794/
https://ncbi.nlm.nih.gov/pubmed/14656960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1549503
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