Viability and virulence of pneumolysin, pneumococcal surface protein A, and pneumolysin/pneumococcal surface protein A mutants in the ear

OBJECTIVE: To determine viability and virulence of Streptococcus pneumoniae mutants deficient in pneumococcal surface protein A (PspA(−)) and pneumolysin (Ply(−)) in the chinchilla ear. Design: Bullae of chinchillas were inoculated bilaterally with wild-type, Ply(−), PspA(−), and Ply(−) /PspA(−) str...

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Detalhes bibliográficos
Main Authors: Schachern, Patricia A, Tsuprun, Vladimir, Goetz, Sarah, Cureoglu, Sebahattin, Juhn, Steven, Briles, David E, Paparella, Michael M, Ferrieri, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037925/
https://ncbi.nlm.nih.gov/pubmed/24051749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoto.2013.4104
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